Johns Hopkins Schools of Public Health and Medicine
CIPHER Lab is a multidisciplinary research team housed within the Johns Hopkins Schools of Public Health and Medicine. Our faculty, researchers, and trainees develop policy-relevant models of infectious disease dynamics to support public health decision-making in the United States and globally.
By integrating epidemiologic data, mathematical modeling, simulation, and statistical inference, we generate actionable evidence on disease transmission, prevention, treatment, and population health outcomes. Our work bridges research and practice, providing insights that help public health agencies, healthcare systems, and policymakers respond to current and emerging health challenges.
Decision support in practice
Recent JHEEM analyses estimate how federal HIV program disruptions could alter incidence by place. The figure below curates headline geographic findings from those papers as one example of how CIPHER turns model output into interpretable public-health evidence.
NBC News · September 2025
Dr. Anthony Fojo discusses how eliminating the CDC's HIV-prevention division could disrupt critical functions, with models projecting over 213,000 additional infections through 2030.
High-burden metropolitan areas
If federal Ryan White HIV/AIDS Program funding were to end, how many additional HIV infections would follow in the country’s 31 highest-burden metropolitan areas?
additional infections
Projected across 31 high-burden metros from 2025 to 2030.